virus and is surrounded by a
helically arranged protein coat. The protein coat
makes up about 95 percent of the mass of this
type of virus. Rabies and mumps are caused by
helical viruses.
The virus that causes
acquired immune deficiency syndrome, or AIDS, is
even more complex. The AIDS virus is shown on the
right. This virus, called the HIV, has two single
strands of RNA in its core. These strands are
surrounded by two layers of protein. A layer of
lipids surrounds these inner protein layers.
Glycoprotein molecules, proteins with sugar
chains attached, are embedded in the lipid layer
and form the capsid of the virus.
Classification
Because viruses are not
considered living things, they are not classified
by the system of nomenclature discussed in
Chapter 18. Viruses instead are classified as DNA
viruses or RNA viruses, depending on the type of
nucleic acid in the capsid. As shown in Table
19-2, viruses contain either RNA or DNA, never
both.
DNA and RNA
Viruses
DNA and RNA viruses
differ in the manner in which they alter the
machinery of a host cell. Once inside the host
cell, a DNA virus may directly produce new RNA
that then makes more viral proteins.
Alternatively the virus DNA may join to the DNA
of the host cell and then direct the synthesis of
new viruses.
RNA viruses perform in
another way. Some RNA viruses enter the cell and
make new proteins directly. They do so by
releasing the RNA, which then migrates directly
to the cytoplasm, where it uses the host
ribosomes to make proteins. The polio virus,
which is an RNA virus, acts in this manner.